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Tacrolimus
Tacrolimus

15.13
Helps balance localized immune responses and relieves chronic skin texture changes.
Ingredient
Tacrolimus
Categories
Autoimmune Support, Skin Care
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Tacrolimus
Reference Brand
Protopic
Product Origin
Generic Product
Reference Manufacturer
Astellas Pharma
Product Form
Ointment, Capsule, Injectable Solution
Regulatory Classification
Rx
Primary Category
Skin Care, Autoimmune Support
Product Category
Calcineurin Inhibitor
Pharmacological Class
Immunosuppressant
Manufacturer Description
Utilized for atopic dermatitis to manage skin inflammation and support lesion healing.
Mechanism of Action
Topical tacrolimus inhibits calcineurin in the skin, which prevents the dephosphorylation of nuclear factor of activated T-cells. This suppresses the activation of T-lymphocytes and the subsequent release of inflammatory cytokines.
Route of Administration
Topical
Onset Time
1–2 weeks
Duration
12–24 hours
Contraindications
Hypersensitivity to tacrolimus, Active skin infection, Netherton's syndrome
Severe Adverse Events
Lymphoma risk, Skin cancer risk, Anaphylaxis — requires immediate medical attention
Common Side Effects
Burning, Stinging, Redness
Uncommon Side Effects
Folliculitis, Acne, Skin tingling
Drug Interactions
Alcohol
Pregnancy Safety Warnings
FDA Category C: Use only if clearly needed. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy established in pediatric patients two years and older for atopic dermatitis.
Storage Guidelines
Store at room temperature; do not freeze.
Related Products
Protopic, Elidel, Prograf
Information related to Tacrolimus is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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