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Letairis
Letairis

13.57
This medication relieves the workload of the heart by promoting optimal vascular relaxation.
Ingredient
Ambrisentan
Category
Heart & Blood Pressure
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Ambrisentan
Reference Brand
Ambrisentan
Product Origin
Generic Alternative
Reference Manufacturer
Gilead Sciences
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Heart & Blood Pressure
Product Category
Endothelin Receptor Antagonist
Pharmacological Class
Selective ET-A Antagonist
Manufacturer Description
Utilized for pulmonary arterial hypertension to manage arterial resistance and support improved exercise capacity.
Mechanism of Action
Ambrisentan selectively antagonizes the endothelin-A (ET-A) receptor in the pulmonary vascular smooth muscle. This blocks the vasoconstricting effects of endothelin, leading to vasodilation and reduced pulmonary blood pressure.
Route of Administration
Oral
Onset Time
4 weeks
Duration
15 hours (half-life)
Contraindications
Pregnancy, Idiopathic pulmonary fibrosis, Hypersensitivity to ambrisentan
Severe Adverse Events
Hepatotoxicity, Fluid retention, Fetal toxicity — requires immediate medical attention
Common Side Effects
Peripheral edema, Nasal congestion, Flushing
Uncommon Side Effects
Anemia, Headache, Sinusitis
Drug Interactions
Alcohol, Cyclosporine, Warfarin, Sildenafil
Pregnancy Safety Warnings
FDA Category X: Strictly contraindicated in pregnancy. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy in children have not been established.
Storage Guidelines
Store at room temperature in original package.
Related Products
Volibris, Tracleer, Opsumit
Information related to Letairis is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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