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Hyzaar
Hyzaar

0.66
Consistent use relieves arterial resistance to promote stable circulatory function.
Ingredients
Losartan, Hydrochlorothiazide
Category
Heart & Blood Pressure
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Losartan, Hydrochlorothiazide
Reference Brand
Cosart-H
Product Origin
Generic Alternative
Reference Manufacturer
Merck Sharp & Dohme
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Heart & Blood Pressure
Product Category
Angiotensin II Receptor Antagonist, Thiazide Diuretic
Pharmacological Class
ARB/Thiazide Combination
Manufacturer Description
Formulated for hypertension to manage blood pressure levels and support cardiovascular risk reduction.
Mechanism of Action
Losartan blocks the vasoconstrictor effects of angiotensin II by selectively binding to AT1 receptors. Hydrochlorothiazide promotes fluid excretion by inhibiting sodium reabsorption in the distal tubules, providing additive blood pressure reduction.
Route of Administration
Oral
Onset Time
1–2 hours
Duration
24 hours
Contraindications
Hypersensitivity to sulfonamides, Anuria, Pregnancy, Concurrent use of aliskiren in diabetics
Severe Adverse Events
Angioedema, Renal failure, Fetal toxicity — requires immediate medical attention
Common Side Effects
Dizziness, Fatigue, Nasal congestion
Uncommon Side Effects
Muscle cramps, Hyperkalemia, Hypomagnesemia
Drug Interactions
Lithium, Potassium Supplements, NSAIDs, Alcohol, Digoxin
Pregnancy Safety Warnings
FDA Category D: Positive evidence of human fetal risk. Breastfeeding: Not recommended as both components may pass into milk.
Age Restrictions
Safety and efficacy not established in pediatric patients.
Storage Guidelines
Store below 25°C in a dry place.
Related Products
Cosudex, Karvezide, Avapro HCT
Information related to Hyzaar is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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