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Efavirenz
Efavirenz

3.87
Disrupts the reverse transcriptase enzyme to restrict viral replication in the immune system.
Ingredient
Efavirenz
Category
HIV Management
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Efavirenz
Reference Brand
Sustiva
Product Origin
Generic Product
Reference Manufacturer
Merck Sharp & Dohme
Product Form
Tablet, Capsule
Regulatory Classification
Rx
Primary Category
HIV Management
Product Category
Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
Pharmacological Class
Antiretroviral
Clinical Indications
Hiv-1 infection
Manufacturer Description
Utilized for hiv-1 infection to manage viral replication and support immune system health.
Mechanism of Action
Efavirenz binds non-competitively to HIV-1 reverse transcriptase. This action blocks the RNA-dependent and DNA-dependent DNA polymerase activities of the enzyme, inhibiting the viral replication cycle.
Route of Administration
Oral
Onset Time
2–4 weeks
Duration
40–55 hours (half-life)
Contraindications
Hypersensitivity to efavirenz, Concurrent use of voriconazole, Concurrent use of elbasvir/grazoprevir
Severe Adverse Events
Psychosis, Hepatotoxicity, Suicidal ideation — requires immediate medical attention
Common Side Effects
Dizziness, Vivid dreams, Insomnia
Uncommon Side Effects
Rash, Fatigue, Nausea
Drug Interactions
Alcohol, Voriconazole, Simvastatin, Ritonavir, Oral Contraceptives
Pregnancy Safety Warnings
FDA Category D: High risk of neural tube defects. Breastfeeding: Not recommended for HIV-positive mothers.
Age Restrictions
Safety and efficacy established in pediatric patients three months and older.
Storage Guidelines
Store at room temperature.
Related Products
Stocrin, Sustiva, Edurant
Information related to Efavirenz is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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