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Donepezil
Donepezil

0.7
Enhancing cholinergic transmission helps with cognitive focus and memory function.
Ingredient
Donepezil
Category
Neurology
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Donepezil
Reference Brand
Aricept
Product Origin
Generic Product
Reference Manufacturer
Pfizer
Product Form
Tablet, Orally Disintegrating Tablet
Regulatory Classification
Rx
Primary Category
Neurology
Product Category
Cholinesterase Inhibitor
Pharmacological Class
Piperidine Derivative
Clinical Indications
Alzheimer's disease
Manufacturer Description
Utilized for alzheimer's disease to manage cognitive symptoms and support functional independence.
Mechanism of Action
Donepezil reversibly and non-competitively inhibits the enzyme acetylcholinesterase. This increases the concentration of acetylcholine in the brain, enhancing cholinergic neurotransmission and alleviating symptoms of dementia.
Route of Administration
Oral
Onset Time
2–4 weeks
Duration
70 hours (half-life)
Contraindications
Hypersensitivity to donepezil, Hypersensitivity to piperidine derivatives
Severe Adverse Events
Bradycardia, Gastrointestinal hemorrhage, Seizures — requires immediate medical attention
Common Side Effects
Nausea, Diarrhea, Insomnia
Uncommon Side Effects
Muscle cramps, Fatigue, Anorexia
Drug Interactions
Alcohol, Ketoconazole, Quinidine, Phenytoin, Anticholinergics
Pregnancy Safety Warnings
FDA Category C: Use only if benefit outweighs risk. Breastfeeding: Excretion in milk is unknown.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store at room temperature.
Related Products
Aricept, Exelon, Reminyl
Information related to Donepezil is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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