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Chlorambucil
Chlorambucil

3.12
Routine use helps reduce abnormal malignant cell proliferation throughout the blood and lymphatic systems.
Ingredient
Chlorambucil
Category
Oncology Support
Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Chlorambucil
Reference Brand
Leukeran
Product Origin
Generic Product
Reference Manufacturer
Aspen Pharmacare
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Oncology Support
Product Category
Antineoplastic
Pharmacological Class
Alkylating Agent
Manufacturer Description
Indicated for chronic lymphocytic leukemia and lymphoma to manage malignant cell growth and support oncology care.
Mechanism of Action
Chlorambucil is a nitrogen mustard derivative that acts as a bifunctional alkylating agent. It attaches alkyl groups to DNA, causing cross-linking and permanent damage that inhibits DNA replication and cellular proliferation.
Route of Administration
Oral
Onset Time
3–4 weeks
Duration
Variable
Contraindications
Hypersensitivity to chlorambucil, Pregnancy, Resistance to previous alkylating therapy
Severe Adverse Events
Myelosuppression, Secondary malignancy, Pulmonary fibrosis — requires immediate medical attention
Common Side Effects
Nausea, Vomiting, Anorexia
Uncommon Side Effects
Stomatitis, Fatigue, Rash
Drug Interactions
Alcohol, Live Vaccines, Phenytoin, Warfarin
Pregnancy Safety Warnings
FDA Category D: High risk of fetal toxicity. Breastfeeding: Not recommended.
Age Restrictions
Safety and efficacy in pediatric patients have not been established.
Storage Guidelines
Store in the refrigerator (2°C to 8°C).
Related Products
Leukeran, Cyclophosphamide
Information related to Chlorambucil is compiled and periodically reviewed with reference to established medical sources and prescribing guidance. Content is provided for general reference and should be confirmed with a registered healthcare professional before use.
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